Thomas M. Hyde, M.D., Ph.D., is the Chief Operating Officer of the Lieber Institute for Brain Development. As such, he directly oversees all functions of the Central Administrative Division, including personnel, finance, information technology, facilities, contracts, and affiliations with outside organizations. In addition to his administrative portfolio, Dr. Hyde manages the Institute’s collection of postmortem human brain samples. His research focuses on changes in GABA signaling across the stages of normal development and in major psychiatric diseases. Dr. Hyde attended the University of Pennsylvania from 1974–1984. He received a B.A. in Biology in 1978, graduating summa cum laude. He received a joint M.D.-Ph.D. in 1984, with a Ph.D. from the Department of Anatomy. While in this combined degree program, he was the recipient of a University Scholars Award from Penn, and a Medical Scientist Training Program Scholarship from the NIH. He served a general medical internship at the Penn Presbyterian Medical Center from 1984–1985, followed by a neurology residency at Stanford University from 1985–1988. He served as Chief Resident in Neurology the final year of his residency. After leaving California, Dr. Hyde worked in the Clinical Brain Disorders Branch (CBDB) of the intramural program of the National Institute of Mental Health (NIMH). He ran the Neurology Consultation Clinics at St. Elizabeth’s Hospital under the auspices of the NIMH from 1988–1996. From 1996–2010, he worked full-time in the Section on Neuropathology in the CBDB, developing the world’s largest collection of postmortem human brains dedicated to neuropsychiatric disease in general, and schizophrenia in particular.