Category: Research

A Foundation Building Strength (AFBS) is excited to share updates showcasing the significant progress being made in research projects enabled by donor support. We are witnessing meaningful advancements in NM therapies, and our efforts to develop treatments and therapies for Nemaline Myopathy (NM) continue to yield promising results. A Refined Mouse Model for NEB-Related NM…

Unraveling the Mysteries of Nemaline Myopathy: A Transcontinental Effort The quest to understand and treat Nemaline Myopathy (NM) has taken a significant leap forward, thanks to a powerful collaboration between researchers across the globe. Dr. David Mack and his team at the University of Washington, in partnership with Dr. Joshua Clayton from Prof. Nigel Laing’s…

We’re excited to share some encouraging news on the front lines of Nemaline Myopathy research. Dr. Afrooz Rashnonejad and her team, funded by the support of AFBS, have been making strides in developing a potential gene therapy for NEM3, a form of Nemaline Myopathy caused by mutations in the ACTA1 gene. Nemaline Myopathy Gene Therapy:…

Dr. Vandana Gupta and her team at Brigham & Women’s Hospital, with funding from A Foundation Building Strength (AFBS), are making exciting progress in the quest to find treatments for Nemaline Myopathy (NM). This rare neuromuscular disease affects muscle function and can significantly impact quality of life. Here’s a quick update on their recent research…

Nemaline Myopathy (NM) is a rare muscle disorder that weakens the body’s skeletal muscles. Finding effective treatments for NM has been challenging, in part due to the difficulty of recreating the disease in a laboratory setting. However, a recent research project funded by A Foundation Building Strength (AFBS) has made significant progress in overcoming this…

At AFBS, we’re committed to finding treatments for Nemaline Myopathy (NM) through a diverse array of research approaches. From gene therapy to small molecules and disease management strategies, we’re investing in initiatives that hold the most promise for our community and we’re thrilled to share an exciting update on a groundbreaking Nemaline Myopathy exosuit research…

There’s been exciting progress on a new approach treating Nemaline Myopathy (NM), the rare muscle disorder that causes weakness and low muscle tone. While researchers have identified twelve different faulty genes that cause NM and prevent muscles from working properly (ACTA1, NEB, TPM2, TPM3, KBTBD13, CFL2, KLHL40, KLHL41, LMOD3, MYPN, TNNT1, and TNNT3, with the…