Our mission is to find treatments for Nemaline Myopathy.

Nemaline Myopathy

is a group of congenital, hereditary neuromuscular disorders that cause muscle weakness, generally nonprogressive, of varying severity where severe forms show up to 66% mortality rates before the age of two. It is considered one of the most severe muscle conditions of childhood. Currently no treatments or disease modifying therapies exist for nemaline myopathy and few potential candidate drugs have been identified.

Our Foundation

A Foundation Building Strength is a non–profit organization dedicated to finding treatments for Nemaline Myopathy.

We do this by funding research aimed at understanding protein function and disease progression, prerequisites to regulatory approval such as natural history, and gene expression and editing such as CRISPR, exon skipping, gene therapy, and related approaches.


Request for Proposals

Building Strength 2017

AFBS is excited to announce a new initiative to fund up to $1 million in research grants, advancing our mission to find treatments for NM. AFBS has and will continue to fund research advancing our understanding of the pathogenesis of NM. We have started to fund studies looking at some promising treatment approaches.

Learn More about the RFP

Upcoming Events

  • LoveLiv Cycle for Strength 2017

    March 5 @ 3:00 pm - 4:30 pm

    For the 5th annual LoveLiv fundraiser benefitting a Foundation Building Strength, we’re having a SoulCycle ride and raising money for critical...